Exome Genome Reanalysis Policy

Overview

In certain cases, authorized ordering providers may request a complimentary reanalysis of exome and genome (including RISE) sequencing results.

Such a re-evaluation of previously generated sequencing data could incorporate new clinical phenotypes, updated variant classifications, and advances in gene-disease knowledge. No new sequencing is performed during reanalysis; the analysis is limited to the original dataset.

Representation of reanalysis of either exome or genome sequencing data. Exome (left) is represented by a magnifying glass focused on a segment of a DNA helix. Arrow points toward Reanalysis. Reanalysis (middle) is represented by connecting the dots between the other two symbols. Genome is represented by a pair of chromosomes. Arrow points toward Reanalysis.

Reanalysis Process

Request

Reanalysis requests may be submitted via the client portal or test requisition form. Inclusion of relevant patient information to identify the original test is required. This may include patient demographics, Fulgent test ID, or a copy of the original test.

Analysis

If the request is confirmed as eligible, Fulgent will conduct the reanalysis and provide a new report detailing any updates to genetic interpretations or identified variants. Confirmatory studies may be included in this process if they are deemed to be within the scope of reanalysis service and there is an available sample.

Fees and Billing

Reanalysis is complimentary once per patient within two years of the original test report date. If the patient previously had multiple exome/genome tests performed, only one is eligible for reanalysis free of charge.

Eligibility and Limitations

Reanalysis service is defined as a re-assessment of existing NGS data from a previously completed test order. This reanalysis may include review of genes and variants previously reported or new genes and variants not previously reported.

Reanalysis does not apply to cases where a new specimen is required for analysis and does not include any new analysis that was not included in the previous test order.
No new genomic sequencing data will be generated, and addition of mitochondrial, repeat disorders, PGx (pharmacogenetic testing), or RNA-seq (RISE) cannot be added if it was not included on the original test performed.

The policy applies to all exome and genome sequencing services, including RNA-seq/RISE, performed by Fulgent Genetics.
This policy is available to all authorized ordering providers who have received sequencing results of the eligible tests directly from Fulgent within two years of the original report date.
All complimentary exome/genome reanalysis requests are subject to Laboratory approval.

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Exome and Genome Reanalysis Policy

Overview

Reanalysis Process

Exome and Genome
Reanalysis Policy