
Full Insight When Every Detail Matters
FulGenome is a next-generation whole genome sequencing (WGS) solution designed to provide comprehensive genomic insights through a single, streamlined report. Leveraging advanced sequencing technology and our proprietary bioinformatics pipeline, FulGenome delivers enhanced variant detection, including single nucleotide variants (SNVs), copy number variants (CNVs), genome-wide del/dups, mitochondrial genome alterations, and repeat expansions.
The optional addition of RNA analysis (RISE) enables deeper characterization of functional impact, providing a powerful tool for clinicians.
Features
- 3-5 week turnaround time
- Multi-variant analysis
- Single, integrated report
Variant Detection
- Single nucleotide variants (SNVs)
- Copy number variants (CNVs)
- Genome-wide del/dups
- Mitochondrial genome alterations
- Repeat expansions
Who is FulGenome for?

What Sets Us Apart
PCR-Free NGS Advantage
Provides more uniform coverage and reduces amplification bias from traditional PCR-based library preparation, leading to higher accuracy in variant calling.
Exceptional Resolution
Detects CNVs with >2 exon resolution and genome-wide del/dups, surpassing traditional exome sequencing.
Enhanced Diagnostic Yield
Whole genome sequencing has been shown to improve positive diagnostic rates compared to exome by capturing non-coding variants beyond +/- 20 intronic junctions, mitochondrial genome variants, and structural changes often missed in exome-based approaches.
Integrated RNA Analysis
Provides functional insights into genetic variants, enabling deeper characterization of pathogenicity. Detects aberrant gene expression, mono-allelic gene expression, and aberrant splicing of expressed target genes.
Streamlined Reporting
Unlike traditional testing requiring multiple separate analyses, FulGenome consolidates key insights into a single, comprehensive report.
Flexible Options
Add on ACMG secondary findings, LP/P only analysis, duo/trio analysis*, and/or complimentary PGx analysis as needed.
SUPPLEMENTAL TESTING
Discover RNA-Integrated Sequence Evaluation (RISE)
RISE integrates whole exome or genome sequencing with RNA sequencing to enhance diagnostic accuracy for complex or undiagnosed cases. By evaluating the RNA-level effects of genetic variants, including those in coding, splice site, and regulatory regions, RISE maximizes clinical insights.
Benefits of RISE
TEST DETAILS
Whole genome sequencing (WGS) using next-generation sequencing (NGS) technology to deliver enhanced variant detection, including single nucleotide variants (SNVs), copy number variants (CNVs), genome-wide del/dups, mitochondrial genome alterations, and repeat expansions.
- Mean Coverage: ~30x
- Turnaround Time: 3-5 weeks
SPECIMEN REQUIREMENTS
1 x EDTA (purple top) tube
1 - 4 mL whole blood in EDTA/purple top tubes
1 x PAXgene Blood RNA Tube*
2.5 mL whole blood in PAXgene blood RNA Tube
*Only required for RISE orders
FULGENOME REPORTS
Fulgent's FulGenome report integrates DNA sequencing, genome-wide del/dups, mitochondrial genome sequencing, and RNA analysis.

How to Order
Collect Sample
Request a kit. Fulgent provides specimen collection kits to clinicians.
Complete TRF
Download and fill out the
test requisition form (TRF) or order through your Fulgent provider portal.
test requisition form (TRF) or order through your Fulgent provider portal.
Ship
Send specimen and completed TRF with the provided shipping material/label as soon as possible.
Receive Report
Results will be available in 3-5 weeks (from lab receipt of sample).
Frequently Asked Questions
What is FulGenome's intended use?
What variant types are covered by FulGenome?
How do I order RISE with FulGenome?
Explore Our Full Genomic Testing Suite
Contact Us
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